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Why was I given metformin for PCOS when I'm not diabetic? Does it help with getting pregnant?

Shruti9h ago

My gynaecologist prescribed metformin along with lifestyle changes. I'm not diabetic and I'm worried about taking a sugar medicine. Will it help me conceive?

1 answer

Nandini G.

1h ago

Metformin is a diabetes medicine, but it's also used in PCOS because many women with PCOS have insulin resistance, even with normal blood sugar. Insulin resistance can raise insulin levels, which in turn can increase male-type hormones and disturb ovulation. Metformin improves how the body responds to insulin, which in some women helps periods become more regular. For fertility specifically, current evidence suggests metformin on its own is less effective at inducing ovulation than medicines such as letrozole. It may be used alongside them, for women with insulin resistance or a higher BMI, or in IVF for some women with PCOS to reduce the risk of OHSS. Whether it's right for you depends on your weight, blood tests and treatment plan. Common side effects are stomach upset, nausea, loose stools and a metallic taste. These often settle over a few weeks, and doctors usually start with a low dose and increase gradually. Taking it with meals helps. Long-term use can lower vitamin B12 levels, so ask your doctor whether this should be checked. Don't start, stop or change the dose without speaking to your doctor. Seek medical attention if you have severe vomiting, abdominal pain, unusual muscle pain or breathlessness. Ask your gynaecologist what the goal of metformin is in your case and how long they plan to continue it.

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